The Science

Why are Peptides important?

A peptide is made up of amino acids, naturally occurring proteins that are the building blocks of life. 

Peptides have been of interest to the medical and pharmaceutical sector because of their role in wound healing and skin care and have been researched extensively. In particular the combination of peptides used in Stratum C has been shown to nearly double the skin's own production of collagen. This combats the effect of the decline of collagen production in menopausal skin.


The Stratum C skin system uses multiple different combinations of peptides at a concentration of 20% including Matrixyl at 6%. This is combined with regenerating and nourishing ingredients targeting peri-menopausal and menopausal skin.


The first makes your muscles tighten. The second stimulates collagen growth. These peptides work together to make the muscles under the skin tighten. This method of flattening facial muscles to reduce fine lines and wrinkles using a topically applied cream or serum is far safer than the invasive procedures such as the paralysis of muscles using Botox injections.

Why Stratum c works

Stratum C relies on clinical and scientific evidence. Our ingredients have been proven in peer reviewed, scientific literature to significantly increase the skin's production of collagen.


The active ingredients in Stratum C have been shown, in studies that I carried out, to increase the production of collagen by skin cells by up to 70%. This is especially important for women going through menopause, which has been shown to suppress the body’s natural collagen production leading to premature ageing of the skin.” 

Prof Ian W Hamley

Diamond Professor of Chemistry, University of Reading .

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Images taken from in house data on file, Forme Labs Ltd.

the route to Hydration

These active ingredients have been combined with a high quality cosmetic grade Hyaluronic Acid and Squalane which are naturally occurring cellular lubricants shown in clinical studies to improve skin elasticity, suppleness and hydration.


The base moisturisers in Stratum C are natural luxuriant products well known in the beauty industry including Jojoba Oil, Seaweed Extract and Apricot Oil. The latter is an excellent source of Vitamin A and E, two important vitamins which are lost during menopause.


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Prof Ian W Hamley

The lack of oestrogen during the menopause leads to a loss in collagen which in turn causes the skin to become thinner and less elastic. The loss in elasticity means we are left with expression lines and wrinkles around the forehead, mouth and particularly the eyes where the skin is more delicate. 

In house data on an anti-wrinkle test in 10 healthy female volunteers has shown up to a 45% reduction in wrinkles after 28 days when using Stratum C Protect Cream containing the all important peptide, Matrixyl at a unique concentration of 6%. 

The photograph opposite shows results of topographical analysis taken from silicon imprints of skin around the eyes pre-testing and following 28 days of twice daily application of Stratum C Protect Cream.  The silicon imprint from 28 days (top right hand corner) shows a flattened outline compared to the pre-testing, 0 day image (top left corner picture).

Tropical Palm Leaf


1. Molecular Pharmeceutics. 2013 Mar 4;10(3):1063-9. Collagen stimulating effect of peptide amphiphile C16-KTTKS on human fibroblasts. Jones RR, Castelletto V, Connon CJ, Hamley IW.

2.  Skin topographical analysis. Forme Laboratories. Data on file

3.  Journal of Drugs in Dermatology. 2011 Sep;10(9):990-1000. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Pavicic T et al.

4.  Journal of Investigative Dermatology. 1999 Nov;113(5):740-6. Absorption of Hyaluronic acid applied to the surface of intact skin. Brown TJ, Alcorn D, Fraser JR.